What is TB-500?

What the name refers to

TB-500 is a name used in the research chemical trade for a synthetic peptide fragment. It is not a brand name issued by a pharmaceutical company, and it is not a drug name recognized by any national medicines regulator. It is a label that sellers apply to a product.

That distinction matters practically. When a compound has an approved name, there is a document behind it specifying what is in the vial, how pure it is, and what testing was done. TB-500 has no such document. What is in a given vial is whatever the supplier put there, and the only evidence of identity or purity is whatever certificate the supplier chooses to provide.

It is sold as a dry powder that has been freeze dried. The powder is stable in that form. It becomes a solution when bacteriostatic water is added, which is the step this page is built around.

Regulatory status

TB-500 is not approved by any regulator for human use. There is no approved label, no approved indication, and no approved dose. It is not a prescription medicine anywhere, and it is not a dietary supplement.

Products sold under this name are typically labeled for laboratory or research use only. That label is a legal position taken by the seller, not a statement about quality. It also means the product was never manufactured under the controls that apply to injectable medicines.

Because it is unapproved, no regulator has reviewed safety data for it, and there is no authority you can appeal to for a correct dose. Anyone stating a specific amount is repeating a number from a forum or a product listing, not from a regulatory review.

What is not known about timing

This site holds no reliable human pharmacokinetic data for TB-500. We make no claim about its half life, how long it takes to clear the body, or whether repeated administration causes it to accumulate.

This is not a hedge. Half life numbers for TB-500 circulate widely, but we cannot trace them to data we can verify, so we do not print them. A figure that cannot be sourced is not more useful for being stated confidently.

The consequence is that this site cannot help you decide how often to administer anything. The arithmetic here concerns concentration and volume only. Those are fixed by the mass in the vial and the water added, and they do not depend on any biological assumption.

Reading the concentration table

The table on this page shows every combination of the vial sizes sold and the water volumes commonly used. Three things in it are worth noticing.

First, the number on the vial does not change when you add water. A 5 mg vial contains 5 mg of peptide whether it is reconstituted with 1 mL or 3 mL. Water changes only how spread out that mass is.

Second, different combinations land on the same concentration. A 5 mg vial in 1 mL and a 10 mg vial in 2 mL both give 5 mg/mL. Concentration is mass divided by volume, so any pair that divides to the same figure behaves identically at the syringe. This is why a volume copied from someone else is meaningless without knowing both their vial size and their water volume.

Third, larger water volumes give figures that do not divide cleanly. A 2 mg vial in 3 mL gives 0.67 mg/mL, and a 10 mg vial in 3 mL gives 3.33 mg/mL. Both are rounded. More water on a small vial makes the measured volume larger and easier to read on a syringe, but leaves an awkward concentration to work with. Less water gives a tidier concentration and a smaller volume, which is harder to measure accurately. That trade is the whole decision.

What this page does not answer

This site has no medical review. It does not tell you whether TB-500 works, what it does in the body, whether it is safe, or what side effects occur. Those are clinical questions, and answering them would require evidence and review that this site does not have.

Amounts of 1, 2, 2.5 and 5 mg appear in product listings. Listing them describes what is being sold. It is not a recommendation, and their presence in commerce is not evidence that any of them is appropriate.

What the calculator does is arithmetic. Given a vial size and a water volume, it returns the concentration of the resulting solution. That result is correct as division. It says nothing about whether the compound is appropriate for any use. For a clinical answer, ask a clinician who can see your situation.

What we do not know

We hold no reliable human pharmacokinetic data for TB-500, so this site makes no claims about its half life, how long it takes to clear, or how it accumulates. The arithmetic below concerns concentration and volume only.

This page answers arithmetic and handling questions. It does not tell you what dose to take, what to expect, or whether anything is appropriate for you, and there is no medical review behind it.

Common questions

Is TB-500 approved by the FDA?

No. TB-500 is not approved by any regulator for human use. There is no approved label, indication or dose. Products sold under this name are usually labeled for research use only.

How much bacteriostatic water should I add to a TB-500 vial?

There is no correct answer, only a trade off. Volumes of 1, 2 and 3 mL are the ones commonly used, and the table shows the concentration each produces for a 2, 5 or 10 mg vial. Less water gives a tidier concentration and a smaller volume to draw. More water gives a larger, easier to read volume at the syringe.

Does adding more water make the dose weaker?

Not by itself. The vial holds the same mass of peptide regardless of the water added. More water lowers the concentration, so the same volume drawn contains less peptide. The mass administered depends on both the concentration and the volume drawn.

What is the half life of TB-500?

We do not publish one. There is no reliable human pharmacokinetic data that we can verify, so this site makes no claim about half life, clearance or accumulation. Figures found elsewhere may not be traceable to a source.

Why do a 5 mg vial in 1 mL and a 10 mg vial in 2 mL match?

Because concentration is mass divided by volume, and both divide to 5 mg/mL. The vials hold different total amounts, so one runs out sooner, but each millilitre drawn from either is identical.

Can this site tell me if TB-500 is safe?

No. This site has no medical review and does not answer clinical questions. It does not assess safety, effectiveness or side effects. It performs concentration arithmetic and nothing more.