What a MOTS-c dose actually costs

Cost per dose is not price per milligram

Sellers quote a vial price. Buyers translate that into price per milligram and stop there. That translation only holds if every milligram in the vial ends up in a dose.

A vial is a closed container. Once it is reconstituted, the peptide inside is committed to that vial. If your dose size does not divide into the vial contents cleanly, the remainder sits there as a partial dose. It was paid for. It is not usable at the dose you chose without opening a second vial.

So the honest arithmetic is: vial price divided by the number of whole doses you can draw. The table on this page gives you that denominator for MOTS-c at the dose sizes that actually appear in listings. Supply your own price and the division is one step.

What the table shows

Two things are worth noticing.

First, the 10 mg vial at a 10 mg dose is the clean case. One vial, 1 whole dose, 0 mg stranded, 0% wasted. There is no remainder to reason about, because the dose and the vial are the same size. Every milligram you bought goes into the single dose.

Second, the 5 mg vial at a 10 mg dose produces 0 whole doses. The dose is larger than the vial. All 5 mg is stranded, and the wasted column reads n/a rather than a percentage. That is not a formatting gap. A waste percentage is a fraction of what you managed to use, and if you drew zero doses from the vial there is nothing to take a fraction of. The 5 mg is not wasted in the sense of being thrown away, it is simply insufficient on its own.

The practical reading: at a 10 mg dose, the vial size decides whether you have a cost per dose at all. With a 5 mg vial you have a cost per vial and no dose.

Water volume changes the syringe reading, not the cost

Listings show MOTS-c reconstituted with 1 mL, 2 mL or 3 mL of bacteriostatic water. It is a common assumption that more water stretches a vial further. It does not.

The water is a carrier. A 10 mg vial holds 10 mg whether you put 1 mL, 2 mL or 3 mL into it. What changes is concentration, and therefore how far up the syringe barrel a given dose sits. More water means a larger volume for the same milligram amount, which some people find easier to measure accurately. It does not create additional peptide.

This matters for cost because it removes one variable. Whatever reconstitution volume you see quoted alongside a price, the doses-per-vial figure in the table is unchanged. Compare vial sizes and dose sizes. Ignore the water when calculating cost.

What this page does not tell you

There is no reliable human pharmacokinetic data for MOTS-c. This site therefore makes no claim about its half life, how long it takes to clear, or whether it accumulates with repeated administration. Anything on this page concerns concentration, volume and division only.

That limitation has a direct effect on cost analysis. A full cost model would include how often a dose is taken, and frequency depends on how a compound behaves over time. We cannot supply that input, so we cannot produce a monthly or annual figure. What we can produce is cost per dose, which is a smaller and more defensible number.

MOTS-c is not approved by any regulator for human use. This site has no medical review process. It does not tell you what dose to take, what to expect, what side effects occur, or whether any of this is safe. Those are questions for a clinician, and the arithmetic here does not substitute for one.

What we do not know

We hold no reliable human pharmacokinetic data for MOTS-c, so this site makes no claims about its half life, how long it takes to clear, or how it accumulates. The arithmetic below concerns concentration and volume only.

This page answers arithmetic and handling questions. It does not tell you what dose to take, what to expect, or whether anything is appropriate for you, and there is no medical review behind it.

Common questions

Is a 10 mg MOTS-c vial cheaper per dose than a 5 mg vial?

At a 10 mg dose, the 10 mg vial produces 1 whole dose and the 5 mg vial produces 0. That makes cost per dose undefined for the 5 mg vial at that dose size, regardless of its price. Comparison only becomes meaningful once both vial sizes yield at least one whole dose at the dose you are pricing.

Can I combine two 5 mg vials to reach a 10 mg dose?

Arithmetically, 5 mg and 5 mg total 10 mg. The doses-per-vial column on this page assumes one vial at a time, which is why the 5 mg row shows 0 whole doses. Whether combining vials is appropriate, sterile or advisable is a handling and clinical question this site does not answer.

Why does the 5 mg row show n/a instead of a waste percentage?

Waste percentage expresses stranded product as a share of the vial across the doses actually drawn. With 0 whole doses, there is no usable output to compare the remainder against. The 5 mg is fully stranded at that dose size, which is stated in the stranded column instead.

Does using less bacteriostatic water save money?

No. The milligram content of the vial is fixed at purchase. Using 1 mL rather than 2 mL or 3 mL raises concentration and shrinks the injection volume, but the number of whole doses in the vial is unchanged. Reconstitution volume is a measurement convenience, not a cost lever.

How often would a dose be taken?

This site does not say. There is no reliable human pharmacokinetic data for MOTS-c, so we make no claim about half life, clearance or accumulation, and frequency cannot be derived from the arithmetic here. That means we also cannot produce a monthly cost figure.

What dose of MOTS-c should I use?

We do not answer that. The dose amounts on this page are the ones that appear in listings, used as inputs to a division problem. They are not recommendations, and this page has no medical review behind it.