MOTS-c dosage chart: how many units on the syringe

What a unit on the syringe actually measures

A U-100 insulin syringe is marked in insulin units, not milligrams. The markings measure volume. On a U-100 barrel, 100 units is 1 mL, so one unit is one hundredth of a millilitre. That is the only thing the syringe knows.

This matters because a peptide vial is sold by mass. A vial labelled 10 mg contains 10 mg of powder and no liquid. You choose the liquid volume when you reconstitute it. That choice sets the concentration, and the concentration is what links milligrams to units.

The arithmetic is one division and one multiplication. Vial mass divided by water volume gives concentration in mg/mL. Dose divided by concentration gives volume in mL. Multiply by 100 to read it as U-100 units. Every row in the table on this page is that same calculation with different inputs.

Reading the table: three things worth noticing

First, the same dose maps to different unit counts depending on how much water you added. A 5 mg dose from a 10 mg vial is 50 units at 1 mL and 100 units at 2 mL. The milligrams delivered are identical. Only the volume differs. This is the single most common source of dosing error with reconstituted peptides, because a unit count copied from someone else's protocol is meaningless without their water volume attached.

Second, several combinations exceed one syringe barrel. Any volume above 1 mL cannot be drawn in a single pull on a standard U-100 syringe. Those rows are flagged in the table. They require either two draws or a different concentration. Splitting a single dose across two injections adds handling steps and adds chances to lose track of how much went in.

Third, more water is not a refinement. Diluting further spreads the same mass over more volume, which pushes unit counts up and can push them past the barrel. Less water concentrates the solution and compresses the dose into fewer units, where each unit mark carries more milligrams and small reading errors matter more. Neither direction is inherently better. The volume that keeps your intended dose comfortably inside one barrel, on marks you can read, is the practical one.

What this page does not tell you

MOTS-c is not approved by any regulator for human use. There is no established human dose, no dosing schedule with an evidence base behind it, and no clinical guidance to reproduce here.

The dose figures used on this page were taken from what vendors list. That is a description of a market, not a recommendation. A number appearing in a listing tells you nothing about whether it is appropriate, effective or safe for any person.

This site has no medical review process. It will not tell you what dose to take, what to expect, what side effects occur, or whether MOTS-c does anything. Those are clinical questions and this is a calculator. If you want an answer to them, ask someone qualified to give one.

No reliable human pharmacokinetic data

There is no dependable human pharmacokinetic data for MOTS-c. This site therefore makes no claim about its half life, how quickly it clears, whether it accumulates across repeated doses, or how long any dose remains present.

That gap has a direct consequence for how you should read the table. Concentration and volume arithmetic is exact and verifiable. Timing arithmetic is not available, because the inputs it would need do not exist in reliable form. Anyone presenting a MOTS-c dosing frequency as pharmacokinetically justified is filling that gap with assumption.

So the table answers one narrow question: given this vial, this water volume and this dose in milligrams, what do I draw to. It does not address how often, for how long, or in what pattern.

What we do not know

We hold no reliable human pharmacokinetic data for MOTS-c, so this site makes no claims about its half life, how long it takes to clear, or how it accumulates. The arithmetic below concerns concentration and volume only.

This page answers arithmetic and handling questions. It does not tell you what dose to take, what to expect, or whether anything is appropriate for you, and there is no medical review behind it.

Common questions

How many units is 5 mg of MOTS-c?

It depends entirely on the water volume. From a 10 mg vial in 1 mL, 5 mg is 50 units on a U-100 syringe. From the same vial in 2 mL, the same 5 mg dose is 100 units. The unit count is a volume, so it only means something alongside the concentration it came from.

Does adding more bacteriostatic water reduce the dose?

No. The vial contains a fixed mass of peptide and water does not change it. More water lowers the concentration, so you draw more volume to deliver the same milligrams. The number on the barrel goes up while the dose stays the same.

Why do some rows say "over one barrel"?

A standard U-100 insulin syringe holds 100 units, which is 1 mL. Any dose requiring more than 1 mL of solution cannot be drawn in one pull. Those rows would need multiple draws or a lower water volume to fit inside a single barrel.

How much water should I add to a MOTS-c vial?

There is no correct answer, only trade-offs the arithmetic makes visible. Less water means fewer units per dose and coarser resolution on the barrel. More water means finer resolution but larger volumes that can exceed one barrel. Pick the volume that puts your intended dose on marks you can read clearly within a single draw.

How often should MOTS-c be injected?

This page cannot answer that. There is no reliable human pharmacokinetic data for MOTS-c, so no claim about half life, clearance or accumulation can be supported here. Frequency is a clinical question and this site has no medical review.

Does a U-40 or 1 mL non-insulin syringe change the numbers?

The volume required does not change, but the markings do. All figures on this page assume a U-100 syringe, where 100 units equals 1 mL. Reading a U-100 unit count off a differently graduated barrel will give you the wrong dose.